Article

Mitochondrial Dysfunction: A New Hallmark in Hereditable Thoracic Aortic Aneurysm Development

2025-02-11

Abstract excerpt

Thoracic aortic aneurysms (TAA) pose a significant health burden due to their asymptomatic progression, often culminating in life-threatening aortic rupture, and the lack of effective pharmacological treatments. Risk factors include elevated hemodynamic stress on the ascending aorta, frequently associated with hypertension and hereditary genetic mutations. Among hereditary causes, Marfan syndrome is the most preva...

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Literature Corpus work: bae4694c-dd36-5613-9395-0c1050d01f69
DOI: 10.20944/preprints202502.0855.v1

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