Article
Arterial remodeling: the role of mitochondrial metabolism in vascular smooth muscle cells.
American journal of physiology. Cell physiology - 1 Jan 2023
Qin Hua-Li, Bao Jing-Hui, Tang Jian-Jun, Xu Dan-Yan, Shen Li
Abstract excerpt
Arterial remodeling is a common pathological basis of cardiovascular diseases such as atherosclerosis, vascular restenosis, hypertension, pulmonary hypertension, aortic dissection, and aneurysm. Vascular smooth muscle cells (VSMCs) are not only the main cellular components in the middle layer of the arterial wall but also the main cells involved in arterial remodeling. Dedifferentiated VSMCs lose their...
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