Article

Single-Cell RNAseq analysis of infiltrating neoplastic cells at the migrating front of human glioblastoma

2017-07-19

Abstract excerpt

<h4>Summary</h4> Glioblastoma is the most common primary brain cancer in adults and is notoriously difficult to treat due to its diffuse nature. We performed single-cell RNAseq on 3589 cells in a cohort of four patients. We obtained cells from the tumor core as well as surrounding peripheral tissue. Our analysis revealed cellular variation in the tumor’s genome and transcriptome, We were able to identify infiltra...

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Literature Corpus work: 6b133598-2a05-54be-bd68-55e7d1f39b86
DOI: 10.1101/165811

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