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Identification of an epigenetically and phenotypically distinct peritumoral glioblastoma cell population linked to inferior patient outcome

2026-01-17

Abstract excerpt

<h4>ABSTRACT</h4> Glioblastoma (GB) is an aggressive and therapy-resistant primary brain tumor with dismal prognosis. Lethality is in most patients caused by a local peritumoral (Edge) relapse near the resection cavity. This region is insufficiently studied and experimental models are scarce. We have analyzed matched tissue samples and cell cultures from bulk tumors and Edge regions of 11 GB patients. Genomic pro...

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Literature Corpus work
82d23848-d72b-56aa-9889-2e6d1a419476
DOI
10.64898/2026.01.16.699862
Open publication

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Identification of an epigenetically and phenotypically distinct peritumoral glioblastoma cell population linked to inferior patient outcomeDOI 10.64898/2026.01.16.699862
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