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Dissecting human gliomas by single-cell RNA sequencing

5 Jul 2017

Abstract excerpt

Diffuse gliomas are the most common human primary brain tumors and remain incurable. They are complex entities in which diverse genetic and nongenetic effects determine tumor biology and clinical course. Our current understanding of gliomas in patients is primarily based on genomic and transcriptomic methods that have profiled them as bulk, providing critical information yet masking the diversity of cells within...

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PMID: 29016805
DOI: 10.1093/neuonc/nox126

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