Article

Single-cell molecular characterization to partition the human glioblastoma tumor microenvironment (TME) genetic background

2022-02-10

Abstract excerpt

Glioblastoma (GB) is a devastating primary brain malignancy. Recurrence of GB is inevitable despite the standard treatment of surgery, chemotherapy, and radiation, and the median survival is limited to around 15 months. Barriers to treatment include the complex interactions among the different cellular components inhabitant of the tumor microenvironment. These challenges are further compounded by extensive inter-...

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Literature Corpus work: 005d89af-0531-51dc-a18a-4c4a43caf1c4
DOI: 10.1101/2022.02.10.479701

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