Article

Characterization of early white matter changes in CADASIL using microscopic diffusion imaging and relaxometry

2023-02-28

Abstract excerpt

<h4>Background and purpose</h4> Cerebral small vessel diseases (SVDs) are characterized by early white matter (WM) changes, whose pathological underpinnings are yet poorly understood. CADASIL is a monogenic and archetypal SVD, providing an ideal model for investigating these changes. Here, we used multicompartment microscopic diffusion imaging and relaxometry to elucidate microstructural changes underlying early...

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Literature Corpus work: 6b0f020c-1bcf-5945-819b-e64e362db791
DOI: 10.1101/2023.02.27.530286

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