Article

<i>APOE ε</i>4 carriage associates with improved myocardial performance in older age

2022-07-21

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Although APOE ε 4 allele carriage confers a risk of coronary disease, its persistence in human populations might be explained by certain survival advantages (antagonistic pleiotropy). <h4>Hypothesis</h4> Combining data from three British cohorts–1946 National Survey of Health and Development (NSHD), Southall and Brent Revised (SABRE) and UK Biobank–we explored whether APOE ε...

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Literature Corpus work: 6af8b9d2-1743-5699-97b9-3f61648806de
DOI: 10.1101/2022.07.20.22277846

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