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Article

Novel Insights into Causal Effects of Serum Lipids and Apolipoproteins on Cardiovascular Morpho-Functional Phenotypes.

Cardiovascular toxicology - 1 Dec 2024

Liu Ankang, Liu Xiaohong, Wei Yuanhao, Xiang Xiqiao, Chen Yi, Zheng Ziwei, Xu Changde, Yang Shaoling, Zhao Kun

Abstract excerpt

Previous observational studies have explored the association between serum lipids, apolipoproteins, and adverse ventricular/aortic structure and function. However, whether a causal link exists is uncertain. This study employed a two-sample Mendelian randomization (MR), colocalization, reverse, and multivariable MR (MVMR) approach to examine the causal associations among five serum lipids, two apolipoproteins, and...

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Identifiers

PMID: 39394502
DOI: 10.1007/s12012-024-09930-w
PMCID: PMC11564402

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