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Primary cilia drive postnatal tidemark patterning in articular cartilage by coordinating responses to Indian Hedgehog and mechanical load

2021-07-04

Abstract excerpt

<h4>ABSTRACT</h4> Articular cartilage (AC) is essential for body movement, but is highly susceptible to degenerative diseases and has poor self-repair capacity. To improve current subpar regenerative treatment, developmental mechanisms of AC should be clarified and, specifically, how postnatal multi-zone organization is acquired. Primary cilia are cell surface organelles crucial for mammalian tissue morphogenesis...

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Literature Corpus work
6ac643eb-2dba-5448-bc82-123ae9c00297
DOI
10.1101/2021.07.04.451018
Open publication

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Primary cilia drive postnatal tidemark patterning in articular cartilage by coordinating responses to Indian Hedgehog and mechanical loadDOI 10.1101/2021.07.04.451018
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