Article

<i>Thm2</i> interacts with paralog, <i>Thm1</i> , and sensitizes to Hedgehog signaling in postnatal skeletogenesis

2020-01-27

Abstract excerpt

Ciliopathies are genetic syndromes that link osteochondrodysplasias to dysfunction of primary cilia. Primary cilia extend from the surface of bone and cartilage cells, to receive extracellular cues and mediate signaling pathways. Mutations in several genes that encode components of the intraflagellar transport-A ciliary protein complex have been identified in skeletal ciliopathies, including THM1 . Here, we repor...

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Literature Corpus work: 5ed90616-ac96-5ed4-9fab-7d0a6af54885
DOI: 10.1101/2020.01.26.920165

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