Function and regulation of primary cilia and intraflagellar transport proteins in the skeleton

Abstract excerpt

Primary cilia are microtubule-based organelles that project from the cell surface to enable transduction of various developmental signaling pathways. The process of intraflagellar transport (IFT) is crucial for the building and maintenance of primary cilia. Ciliary dysfunction has been found in a range of disorders called ciliopathies, some of which display severe skeletal dysplasias. In recent years, interest...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic and Kidney Cyst Diseases
• Share to Renal and related cancers
• Share to Urological Disorders and Treatments