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Primary cilia regulate Meibomian glands development and dimensions without impairing lipid composition of the meibum

2022-05-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> Primary cilia regulate the development of various ectoderm-derived tissues, including the corneal epithelium, skin, hair follicle and sebaceous glands. We aimed to investigate their role in meibomian gland (MG) development. <h4>Methods</h4> Primary cilium ablation in MGs was achieved by crossing a floxed Ift88 mouse ( Ift88 fl/fl ) with a mouse expressing the Cre recombinase...

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Literature Corpus work
b24e0ff0-9264-5bb4-9c34-cc8af5417393
DOI
10.1101/2022.05.16.492188
Open publication

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Primary cilia regulate Meibomian glands development and dimensions without impairing lipid composition of the meibumDOI 10.1101/2022.05.16.492188
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