Article

Regnase-1 deficiency restrains <i>Klebsiella pneumoniae</i> infection by regulation of a Type I interferon response

2021-11-21

Abstract excerpt

Excessive inflammatory responses can cause collateral tissue damage or autoimmune inflammation, sometimes with severe morbidity or mortality. During host defense responses, numerous negative feedback mechanisms are established to prevent excessive unchecked inflammation. However, this restraint can sometimes come at the cost of suboptimal infection control, and we do not fully understand how this balance is mainta...

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Literature Corpus work: 6a47e42b-158c-52c6-800c-7ce93f870811
DOI: 10.1101/2021.11.20.469389

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