Article

<i>Klebsiella pneumoniae</i> T6SS exacerbates gut inflammation promoting tumorigenesis

2026-03-31

Abstract excerpt

<h4>Summary</h4> Dysbiosis and bacterial pathobionts contribute to inflammation in IBD and CRC, yet the molecular drivers of this process remain unclear. We identify the Klebsiella pneumoniae type VI secretion system (T6SS) as a key promoter of intestinal inflammation and tumor progression. Metagenomic analyses revealed enrichment of T6SS encoding genes in the gut microbiota of IBD patients during inflammatory f...

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Literature Corpus work: 696b1bb4-bee5-5a38-bbdc-4b509fac981d
DOI: 10.64898/2026.03.31.715367

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