Article
Expanding the CRISPR Toolbox with ErCas12a in Zebrafish and Human Cells
2019-05-25
Abstract excerpt
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR associated (Cas) effector proteins enable the targeting of DNA double-strand breaks (DSBs) to defined loci based on a variable length RNA guide specific to each effector. The guide RNAs are generally similar in size and form, consisting of a ~20 nucleotide sequence complementary to the DNA target and an RNA secondary structure recognized...
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Identifiers and source
- Literature Corpus work
- 6a42dfc7-ec6e-55f6-b0e1-3583bd6361ef
- DOI
- 10.1101/650515