Article

Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function

2021-12-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Fibrotic organ responses have recently been identified as long-term complication in diabetes. Indeed, insulin resistance and aberrant hepatic lipid accumulation represent driving features of progressive non-alcoholic fatty liver disease (NAFLD), ranging from simple steatosis and non-alcoholic steatohepatitis (NASH) to fibrosis. Effective pharmacological regimens to stop progr...

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Literature Corpus work: 6a30b9f1-9d46-5644-a3b9-15c3f77f38f1
DOI: 10.1101/2021.12.17.473222

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