Article

Identification and functional characterisation of a rare <i>MTTP</i> variant underlying hereditary non-alcoholic fatty liver disease

2021-07-25

Abstract excerpt

<h4>Background and aims</h4> Non-alcoholic fatty liver disease (NAFLD) is a complex trait that has a global prevalence estimated as 25%. We aimed to identify the genetic variant underlying a four-generation family with progressive NAFLD leading to cirrhosis, decompensation and development of hepatocellular carcinoma in the absence of common risk factors such as obesity and type 2 diabetes. <h4>Methods</h4> Exome s...

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Literature Corpus work: 3716f91d-a418-55b5-83fb-fccf54049b07
DOI: 10.1101/2021.07.22.21260356

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