Article

Holistic Characterization of Single Hepatocyte Transcriptome Responses to High Fat Diet

2020-04-18

Abstract excerpt

During nutritional overload and obesity, hepatocyte function is grossly altered, and a subset of hepatocytes begins to accumulate fat droplets, leading to non-alcoholic fatty liver disease (NAFLD). Recent single cell studies revealed how non-parenchymal cells, such as macrophages, hepatic stellate cells, and endothelial cells, heterogeneously respond to NAFLD. However, it remains to be characterized how hepatocyte...

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Literature Corpus work: 04633bc0-21f7-573f-beb9-c8f0dd105ad7
DOI: 10.1101/2020.04.16.045260

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