Article

Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh Syndrome

2022-02-01

Abstract excerpt

<h4>Summary</h4> Mitochondrial diseases represent a spectrum of disorders caused by impaired mitochondrial function ranging in severity from mortality during infancy to progressive adult-onset disease. Mitochondrial dysfunction is also recognized as a molecular hallmark of the biological aging process. Rapamycin, a drug that increases lifespan and health during normative aging also increases survival and reduces...

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Literature Corpus work: 6a2e56e7-c2ed-59c3-9612-dccd3e843d95
DOI: 10.1101/2022.01.31.478591

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