Article

Inhibition of systemic mammalian metabolism by carnitine mimics from the gut microbiota

2025-11-11

Abstract excerpt

<h4>Background</h4> The gut microbiota and microbiome-derived metabolites are implicated in various aspects of human health. Here we sought to determine the systemic effects, and mechanism of action, of microbiome-derived carnitine analogues in germ free and conventionally colonised mice. <h4>Results</h4> Here we report the systemic localization of the microbiome-derived carnitine analogues, 3-methyl-4-(trimethy...

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Literature Corpus work: 6b8938d4-a5be-5f23-b440-ab9170412aef
DOI: 10.1101/2025.11.11.687811

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