Article

Maltodextrin administration ameliorates brain pathology in a mouse model of mitochondrial disease

2023-06-29

Abstract excerpt

Mitochondrial dysfunction lead to a wide group of progressive and fatal pathologies known as mitochondrial diseases (MD). One of the most common pediatric representation of MD is Leigh Syndrome, affecting 1/40.000 births. LS is characterized by neurodegeneration in specific brain areas, such as brainstem and basal ganglia, and by respiratory and motor alterations. However, the results obtained from clinical trials...

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Literature Corpus work: dfaf535d-202a-5e23-97f9-2ce8f645e364
DOI: 10.1101/2023.06.28.546916

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