Article

Environmental Regulation and Gene-by-Environment Interaction Influence <i>RAP1</i> Activity and its Impact on Gene Expression

2026-05-09

Abstract excerpt

Gene-by-environment (GxE) interactions play a major role in shaping both phenotypic and molecular variation, with important implications for human health and disease. In this study, we used the Doxycycline (Dox) regulated, tetracycline-responsive (Tet-Off) promoter system to sequentially reduce or titrate gene expression levels of the essential yeast transcription factor Repressor Activator Protein 1 ( RAP1 ) si...

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Literature Corpus work: 69ff93fb-04a0-5e27-a8e2-0fca4011a042
DOI: 10.64898/2026.05.06.723246

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