Perturb-seq identifies co-regulated gene programs shaping hematopoietic stem and progenitor cell function

Abstract excerpt

To sustain blood formation, hematopoietic stem and progenitor cells (HSPCs) coordinate a multitude of cell biological processes, from cell cycle control and stress responses to lineage priming. While many genetic regulators of high-level HSPC function have been identified, how HSPCs coordinate more basal cell biological programs, and how such programs relate to stem cell function, remains incompletely understood....

Topics

Open a Topic to create a Post that cites this publication.

• Uncategorized literature

Identifiers and source

Literature Corpus work

228634bf-f839-5e0d-9f40-690d448b9b48

DOI

10.64898/2026.08.27.747033