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Article

One Hand Clapping: detection of condition-specific transcription factor interactions from genome-wide gene activity data.

Nucleic acids research - 1 Oct 2012

Dümcke Sebastian, Seizl Martin, Etzold Stefanie, Pirkl Nicole, Martin Dietmar E, Cramer Patrick, Tresch Achim

Abstract excerpt

We present One Hand Clapping (OHC), a method for the detection of condition-specific interactions between transcription factors (TFs) from genome-wide gene activity measurements. OHC is based on a mapping between transcription factors and their target genes. Given a single case-control experiment...

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Identifiers

PMID: 22844089
DOI: 10.1093/nar/gks695
PMCID: PMC3467085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22844089-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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