Article
Chromatin regulators as capacitors of interspecies variations in gene expression.
Molecular systems biology - 30 Nov 2010
Tirosh Itay, Reikhav Sharon, Sigal Nadejda, Assia Yael, Barkai Naama
Abstract excerpt
Gene expression varies widely between closely related species and strains, yet the genetic basis of most differences is still unknown. Several studies suggested that chromatin regulators have a key role in generating expression diversity, predicting a reduction in the interspecies differences on deletion of genes that influence chromatin structure or modifications. To examine this, we compared the genome-wide...
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