Article
Transient genotype-by-environment interactions following environmental shock provide a source of expression variation for essential genes.
Genetics - 1 Feb 2010
Eng Kevin H, Kvitek Daniel J, Keles Sündüz, Gasch Audrey P
Abstract excerpt
Understanding complex genotype-by-environment interactions (GEIs) is crucial for understanding phenotypic variation. An important factor often overlooked in GEI studies is time. We measured the contribution of GEIs to expression variation in four nonlaboratory Saccharomyces cerevisiae strains responding dynamically to a 25 degrees -37 degrees heat shock. GEI was a major force explaining expression variation,...
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