Article

Paralytic, the <i>Drosophila</i> voltage-gated sodium channel, regulates proliferation of neural progenitors

2019-10-14

Abstract excerpt

Proliferating cells, typically considered “non-excitable,” nevertheless exhibit regulation by bioelectrical signals. Notably, voltage-gated sodium channels (VGSC) that are crucial for neuronal excitability, are also found in progenitors and upregulated in cancer. Here, we identify a role for VGSC in proliferation of Drosophila neuroblast (NB) lineages within the central nervous system. Loss of paralytic (para) ,...

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Literature Corpus work: 6998280a-4e24-5146-830f-ae6a858b8eae
DOI: 10.1101/803288

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