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TMAO and its precursors in relation to host genetics, gut microbial composition, diet, and clinical outcomes: Meta-analysis of 5 prospective population-based cohorts

2022-09-02

Abstract excerpt

<h4>ABSTRACT</h4> Trimethylamine N-oxide (TMAO) is a circulating microbiome-derived metabolite implicated in the development of atherosclerosis and cardiovascular disease (CVD). We investigated whether plasma levels of TMAO, its precursors (betaine, carnitine, deoxycarnitine, choline) and TMAO-to-precursor ratios associate with clinical outcomes, including CVD and mortality. This was followed by an in-depth analys...

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Literature Corpus work
698660e0-e6ed-59d5-af0b-3b37e637d902
DOI
10.1101/2022.09.01.22279510
Open publication

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TMAO and its precursors in relation to host genetics, gut microbial composition, diet, and clinical outcomes: Meta-analysis of 5 prospective population-based cohortsDOI 10.1101/2022.09.01.22279510
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