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Unraveling interindividual variation of trimethylamine N‐oxide and its precursors at the population level

30 Mar 2024

Abstract excerpt

Abstract Trimethylamine N‐oxide (TMAO) is a circulating microbiome‐derived metabolite implicated in the development of atherosclerosis and cardiovascular disease (CVD). We investigated whether plasma levels of TMAO, its precursors (betaine, carnitine, deoxycarnitine, choline), and TMAO‐to‐precursor ratios are associated with clinical outcomes, including CVD and mortality. This was followed by an in‐depth analysis...

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PMID: 38898991
DOI: 10.1002/imt2.183

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