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Article

Association between microbiota-dependent metabolite trimethylamine-N-oxide and type 2 diabetes.

The American journal of clinical nutrition - 1 Sept 2017

Shan Zhilei, Sun Taoping, Huang Hao, Chen Sijing, Chen Liangkai, Luo Cheng, Yang Wei, Yang Xuefeng, Yao Ping, Cheng Jinquan, Hu Frank B, Liu Liegang

Abstract excerpt

Background: The association of trimethylamine-N-oxide (TMAO), a microbiota-dependent metabolite from dietary choline and carnitine, with type 2 diabetes was inconsistent.Objective: We evaluated the association of plasma TMAO with newly diagnosed type 2 diabetes and the potential modification of TMAO-generating enzyme flavin monooxygenase 3 (FMO3) polymorphisms.Design: This was an age- and sex-matched case-control...

Read the complete abstract on PubMed

Topics

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28724646
DOI: 10.3945/ajcn.117.157107

Genes

FMO3

Variants

rs2266782

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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