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Dysbiosis of Gut Microbiota with Increased Trimethylamine N-oxide Level in Patients with Large Artery Atherosclerotic and Cardioembolic Strokes

2020-04-06

Abstract excerpt

<h4>Background: </h4> — With the establishment of the concept of the gut–brain axis, increasing evidence has shown that the gut microbiome plays an important role in the pathogenesis of cardiovascular diseases. Gut bacteria can transform dietary choline, L-carnitine, and trimethylamine N -oxide (TMAO) into trimethylamine, which can be oxidized into TMAO again in the liver and participate in atherogenesis. However,...

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Literature Corpus work
28e837d0-61d2-569a-81ab-97f59472d89e
DOI
10.21203/rs.3.rs-20073/v1
Open publication

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Dysbiosis of Gut Microbiota with Increased Trimethylamine N-oxide Level in Patients with Large Artery Atherosclerotic and Cardioembolic StrokesDOI 10.21203/rs.3.rs-20073/v1
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