Article

Long-term balancing selection in <i>LAD1</i> maintains a missense trans-species polymorphism in humans, chimpanzees and bonobos

2014-06-27

Abstract excerpt

Balancing selection maintains advantageous genetic and phenotypic diversity in populations. When selection acts for long evolutionary periods selected polymorphisms may survive species splits and segregate in present-day populations of different species. Here, we investigate the role of long-term balancing selection in the evolution of protein-coding sequences in the Homo-Pan clade. We sequenced the exome of 20 h...

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Literature Corpus work: 697e58a0-8db6-5617-a54e-1ddcf65cad08
DOI: 10.1101/006684

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