Article

Revisiting the evidence for long-lived balancing selection in humans

2025-11-11

Abstract excerpt

Balancing selection maintains variation in a population longer than expected under neutrality. In humans, there are dozens of tentative candidate loci for balancing selection, but only a handful of well-characterized examples, which are either evolutionarily recent alleles or ancient variants shared across species identical by descent (“trans-species polymorphisms”). Here, we look for evidence of balancing selecti...

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Literature Corpus work: e0bc5a99-000a-53d3-9ef7-3da079684747
DOI: 10.1101/2025.11.10.687682

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