Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphic L1 retrotransposons are frequently in strong linkage disequilibrium with neighboring SNPs.

Gene - 10 May 2014

Higashino Saneyuki, Ohno Tomoyuki, Ishiguro Koichi, Aizawa Yasunori

Abstract excerpt

L1 retrotransposons have been the major driver of structural variation of the human genome. L1 insertion polymorphism (LIP)-mediated genomic variation can alter the transcriptome and contribute to the divergence of human phenotypes. To assess this possibility, a genome-wide association study (GWA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Genome
Share to Genome, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hominidae

Share to Introns

Share to Long Interspersed Nucleotide Elements

Share to Nucleotides

Share to Retroelements

Source

Identifiers

PMID: 24614499
DOI: 10.1016/j.gene.2014.03.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24614499-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphic L1 retrotransposons are frequently in strong linkage disequilibrium with neighboring SNPs.PMID 24614499Read ↗

Linkage disequilibrium and signatures of positive selection around LINE-1 retrotransposons in the human genome.Semantic proximity Read ↗

L1 recombination-associated deletions generate human genomic variation.Semantic proximity Read ↗

Identification and characterization of novel polymorphic LINE-1 insertions through comparison of two human genome sequence assemblies.Semantic proximity Read ↗

Combining in silico and experimental methods to dissect the impact of L1 retrotransposons on the human transcriptomeSemantic proximity Read ↗

High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes.Semantic proximity Read ↗

euL1db: the European database of L1HS retrotransposon insertions in humans.Semantic proximity Read ↗

Human population genetic structure and diversity inferred from polymorphic L1(LINE-1) and Alu insertions.Semantic proximity Read ↗

LINE-1 elements in structural variation and disease.Semantic proximity Read ↗

Extensive individual variation in L1 retrotransposition capability contributes to human genetic diversity.Semantic proximity Read ↗

A comprehensive identification and annotation of mobile LINE-1 retrotransposons across human reference and personal genomesSemantic proximity Read ↗

Assessment of genetic variation for the LINE-1 retrotransposon from next generation sequence data.Semantic proximity Read ↗

The insertional history of an active family of L1 retrotransposons in humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.