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A sequential, RNA-derived, modified adenosine pathway safeguards cellular metabolism

2024-05-24

Abstract excerpt

<h4>SUMMARY</h4> RNA contains diverse post-transcriptional modifications and its catabolic breakdown yields numerous modified nucleosides that must be properly processed, but the molecular mechanism is largely unknown. Here, we show that three RNA-derived modified adenosines, N 6 -methyladenosine (m 6 A), N 6 , N 6 -dimethyladenosine (m 6,6 A), and N 6 -isopentenyladenosine (i 6 A), are sequentially metabo...

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Identifiers and source

Literature Corpus work
e9dd63ff-33c0-51e4-94c9-f8632e51864e
DOI
10.1101/2024.05.23.595515
Open publication

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A sequential, RNA-derived, modified adenosine pathway safeguards cellular metabolismDOI 10.1101/2024.05.23.595515
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