Article

Saccharomyces cerevisiae β-glucan auspiciously improves the response of trained macrophages to severe P. aeruginosa infections.

2024-01-18

Abstract excerpt

<title>Abstract</title> Objective P. aeruginosa (PA), the major pathogen of lung cystic fibrosis (CF), polarizes macrophages into hyperinflammatory tissue damaging phenotype. The main aim of this study was to verify whether training of macrophages with β-glucan (BG) might improve their response to <italic>P. aeruginosa</italic> infections. Methods To perform this task C57BL/6 mice sensitive to infections wit...

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Literature Corpus work: 69525745-513c-5422-8e53-d2d2a55df374
DOI: 10.21203/rs.3.rs-3856495/v1

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