Article
Biofilm-forming strains of P. aeruginosa and S. aureus isolated from cystic fibrosis patients differently affect inflammatory phenotype of macrophages.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Jun 2023
Ciszek-Lenda Marta, Majka Grzegorz, Suski Maciej, Walczewska Maria, Górska Sabina, Golińska Edyta, Fedor Angelika, Gamian Andrzej, Olszanecki Rafał, Strus Magdalena, Marcinkiewicz Janusz
Abstract excerpt
OBJECTIVE: Lung cystic fibrosis (CF) is characterized by chronic infections and hyperinflammatory response of neutrophils and macrophages. P. aeruginosa (PA) and S. aureus (MSSA, MRSA) are major pathogens of advanced CF. The main goal of this study was to compare the inflammatory phenotype of murine C57BL/6 macrophages exposed to PA57 with that exposed to MSSA60, both strains isolated from the same patient with...
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