Article
A novel mouse model of chronic Pseudomonas aeruginosa infection inducing bronchiectasis-like phenotype.
Animal models and experimental medicine - 1 Jul 2026
Yang Heng, Liu Yang, Wang Yuqing, Wen Yuhua, Chen Yan, Fan Rui, Xu Jiayan, Hu Shunlian, Qian Hao, Jiang Rui, Cao Weijun, Xu Jinfu
Abstract excerpt
BACKGROUND: Given the need to translate basic research into human therapies, the development and refinement of clinically relevant animal models for bronchiectasis are critically important. To date, there are no well-established animal models for bronchiectasis. Thus, our aim was to develop a novel animal model that accurately recapitulates bronchiectasis-like pathologies. METHODS: To address this question,...
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