Article

β-glucan induced trained immunity enhances antibody levels in a vaccination model in mice

2024-04-17

Abstract excerpt

Trained immunity improves disease resistance by strengthening our first line of defense, the innate immune system. Innate immune cells, predominantly macrophages, are epigenetically and metabolically rewired by β-glucan, a fungal cell wall component, to induce trained immunity. These trained macrophages exhibit increased co-stimulatory marker expression and altered cytokine production. Signaling changes from antig...

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Literature Corpus work: 9d97dd96-5a7b-5cab-8ffe-00d31573a451
DOI: 10.1101/2024.04.11.588932

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