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Acidosis regulates immune progression in rheumatoid arthritis by promoting the expression of cytokines and co-stimulatory molecules in synovial fibroblasts

2025-03-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Tissue acidosis is a key characteristic of RA. It remains unclear whether acidosis promotes the formation of the complex adaptive immune landscape mainly characterized by T cell activation in RA by influencing synovial fibroblasts. This study aims to investigate the influence of acidosis on the immune microenvironment of RA by exploring the cytokine secretion an...

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Literature Corpus work
694db58e-cd05-54fb-aacc-e22e2f869cf0
DOI
10.21203/rs.3.rs-5828919/v1
Open publication

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Acidosis regulates immune progression in rheumatoid arthritis by promoting the expression of cytokines and co-stimulatory molecules in synovial fibroblastsDOI 10.21203/rs.3.rs-5828919/v1
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