Article
Two reactive behaviors of chondrocytes in an IL-1β-induced inflammatory environment revealed by the single-cell RNA sequencing
20 Apr 2021
Abstract excerpt
OBJECTIVE: expanded chondrocytes, which were cultured in an interleukin (IL)-1β -induced inflammatory environment. METHOD: , for 13 days and treated with IL-1β for 0, 24, and 48 h. Cells were collected and subjected to single-cell RNA sequencing. Multiple bioinformatics tools were used to determine the signatures that define chondrocyte physiology. RESULTS: Two major cell clusters with distinct expression...
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