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Article

Single cell immunoprofile of synovial fluid in rheumatoid arthritis with TNF-α/JAK inhibitor treatment

2023-07-24

Abstract excerpt

<title>Abstract</title> <p>Increased volume of synovial fluid (SF) with large amounts of immune cells is present in the joint cavity of many patients with rheumatoid arthritis (RA), syndrome of which can be controlled by TNF-α/JAK inhibitors. Here, we applied single-cell RNA sequencing (scRNA-seq) and subsequent validations to profile the cell components, and their crosstalk in SF from RA patients pre-/post-treat...

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Literature Corpus work
162210bf-cef9-5292-a40f-4d11de11f5b1
DOI
10.21203/rs.3.rs-3166544/v1
Open publication

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Single cell immunoprofile of synovial fluid in rheumatoid arthritis with TNF-α/JAK inhibitor treatmentDOI 10.21203/rs.3.rs-3166544/v1
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