Article

Probabilistic classification of gene-by-treatment interactions on molecular count phenotypes

2024-08-06

Abstract excerpt

Genetic variation can modulate response to treatment (G×T) or environmental stimuli (G×E), both of which may be highly consequential in biomedicine. An effective approach to identifying G×T signals and gaining insight into molecular mechanisms is mapping quantitative trait loci (QTL) of molecular count phenotypes, such as gene expression and chromatin accessibility, under multiple treatment conditions, which is te...

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Literature Corpus work: 691c6b31-15ea-5bf3-85ca-2c4a26b73ff1
DOI: 10.1101/2024.08.03.605142

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