Article
Principled multi-omic analysis reveals gene regulatory mechanisms of phenotype variation.
Genome research - 1 Aug 2018
Hanson Casey, Cairns Junmei, Wang Liewei, Sinha Saurabh
Abstract excerpt
Recent studies have analyzed large-scale data sets of gene expression to identify genes associated with interindividual variation in phenotypes ranging from cancer subtypes to drug sensitivity, promising new avenues of research in personalized medicine. However, gene expression data alone is limited in its ability to reveal cis-regulatory mechanisms underlying phenotypic differences. In this study, we develop a...
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