Article

Pleiotropy of autism-associated chromatin regulators

2022-12-07

Abstract excerpt

<h4>ABSTRACT</h4> Gene ontology analyses of high confidence autism spectrum disorder (hcASD) risk genes have historically highlighted chromatin regulation and synaptic function as major contributors to pathobiology. Our recent functional work in vivo has additionally implicated microtubule biology and identified disrupted cellular proliferation as a convergent ASD phenotype. As many chromatin regulators, includi...

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Literature Corpus work: 68cbc5df-216e-57f1-96e4-a435d4064b22
DOI: 10.1101/2022.12.07.519375

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