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Article

Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites.

Molecular biology of the cell - 1 Aug 2016

Park Jae-Sook, Thorsness Mary K, Policastro Robert, McGoldrick Luke L, Hollingsworth Nancy M, Thorsness Peter E, Neiman Aaron M

Abstract excerpt

The Vps13 protein family is highly conserved in eukaryotic cells. Mutations in human VPS13 genes result in a variety of diseases, such as chorea acanthocytosis (ChAc), but the cellular functions of Vps13 proteins are not well defined. In yeast, there is a single VPS13 orthologue, which is required for at least two different processes: protein sorting to the vacuole and sporulation. This study demonstrates that...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27280386
DOI: 10.1091/mbc.E16-02-0112
PMCID: PMC4966984

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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