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Article

The Vps13 Family of Lipid Transporters and Its Role at Membrane Contact Sites.

International journal of molecular sciences - 12 Mar 2021

Dziurdzik Samantha Katarzyna, Conibear Elizabeth

Abstract excerpt

The conserved VPS13 proteins constitute a new family of lipid transporters at membrane contact sites. These large proteins are suspected to bridge membranes and form a direct channel for lipid transport between organelles. Mutations in the 4 human homologs (VPS13A-D) are associated with a number of neurological disorders, but little is known about their precise functions or the relevant contact sites affected in...

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Identifiers

PMID: 33809364
DOI: 10.3390/ijms22062905
PMCID: PMC7999203

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