Article

Alternative splice variants and germline polymorphisms in human immunoglobulin light chain genes

2021-02-06

Abstract excerpt

<h4>ABSTRACT</h4> Immunoglobulin loci are rich in germline polymorphisms and identification of novel polymorphic variants can be facilitated by germline inference of B cell receptor repertoires. Germline gene inference is complicated by somatic hypermutations, errors arising from PCR amplification, and DNA sequencing as well as from the varying length of reference alleles. Inference of light chain genes is even m...

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Literature Corpus work: 6823109a-429c-56c9-bd89-ae5aea97a760
DOI: 10.1101/2021.02.05.429934

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