Article

Per-sample immunoglobulin germline inference from B cell receptor deep sequencing data

2017-11-16

Abstract excerpt

The collection of immunoglobulin genes in an individual’s germline, which gives rise to B cell receptors via recombination, is known to vary significantly across individuals. In humans, for example, each individual has only a fraction of the several hundred known V alleles. Furthermore, the currently-accepted set of known V alleles is both incomplete (particularly for non-European samples), and contains a signific...

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Literature Corpus work: a02acb2d-7918-56bc-8f6e-e774991df809
DOI: 10.1101/220285

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